Journal ID : TRKU-19-03-2021-11449
[This article belongs to Volume - 63, Issue - 04]
Total View : 366

Title : Synthesis, identification and studying biological activity of new sulfamethoxazole derivatives

Abstract :

A novel series of azido sulfamethoxazole derivatives containing 1,2,3-triazole moiety was synthesized from alkyne barbiturate derivatives and azido sulfamethoxazole(1a) [4-Azido-N-(5-methylisoxazol-3-yl) benzenesulfonamide] in the presence of CuCl as a catalyst and cycloaddition of azidealkyne as a key proce and all chemical structure was confirmed utilizing several analytical methods. The target synthesized compounds were screened for their anti- antibacterial activities.

Full article